WARMINSTER, PA and OXFORD, Vereinigtes Königreich – Arbutus Biopharma Corporation (NASDAQ:ABUS) and Barinthus Biotherapeutics plc (NASDAQ:BRNS) have released Phase 2a clinical data from the IM-PROVE II study. It is a combination of Imdusiran, VTP-300 and a nivolumab dosed for significant treatment of hepatitis B antigens (HBsAg) in men with chronic hepatitis B (cHBV) for men .

In the study, virus-uninfected hepatitis B virus patients received 23% of HCV patients, who used combination therapy for a period of 48 hours with one dose of HBsAg. This indicator is golden as a potential indicator for the functioning of management. The American Association for the Study of Liver Diseases (AASLD) presented “The Liver Meeting® 2024”.

Imdusiran, an Arbutus entwickeltes RNAi-Therapeutikum, was created in a user manual, for a durchschnittlichen treatment of the HBsAg-Spiegel führte. In the combination with the T-Zell-stimulierenden immunotherapy VTP-300 from Barinthus Bio and the monoklonal anti-PD-1-Antikörper Nivolumab, teachers are placed in a period of 48 to 48 hours before the Ag test HBs in association with other groups in the study. kein Nivolumab is used.

The management plan which was carried out and which made it possible to obtain optimal immunity against the risk of error was auf a günstiges Sicherheitsprofil hindeutet. Dr. Leon Hooftman, Chief Medical Officer of Barinthus Bio, and Dr. Karen Sims, Chief Medical Officer of Arbutus Biopharma, are optimistic about the potential of the treatment regimens based on preliminary data.

The use of the protein and antigen of the HBV virus makes it possible to reduce the effects of VTP-300 on the first specific antigen immunotherapy, which then makes it possible to reduce the reduction of HBsAg. The combination of these treatments with a lower dosage of Nivolumab can lead to HBV-specific immunity.

Die IM-PROVE II-Studie umfasste zunächst 40 Teilnehmer und wurde später um weitere 22 Teilnehmer in Gruppe C erweitert, die im Fokus der jüngsten Datenveröffentlichung steht.

This detailed information is provided by a press committee of Arbutus Biopharma Corporation and Barinthus Biotherapeutics plc. More and more research and analysis is being carried out, within the langfristige design and security management schemes of the best systems.

In other business, Arbutus Biopharma Corporation was informed of Q2024 results and an underlying Fortschritte review update in its Hepatitis B (HBV) clinical programs. This update was provided by Interim President and CEO Mike McElhaugh, as well as CFO David Hastings. Specific financial resources or specific financial resources are not provided in detail. The companies have been active in pipeline operations and have helped strengthen HBV clinical programs. Arbutus Biopharma’s mission is to ensure that increased risks and unexpected risks are avoided. The Anruf stops with a Fragerunde, the Möglichkeit zum direkten Austausch mit der Unternehmensführung bot. Dies sind Teil der jüngsten Entwicklungen rund um das Unternehmen.

InvestingPro Erkenntnisse

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Trotz der positiven clinical Ergebnisse ist zu beachten, ass Arbutus derzeit not profitabel ist, mit a nem KGV von -9.02 for the letzten 2wölf Monate bis Q3 2024. Dies steht im Einklang mit dem Fokus of Undernehmens auf Forschung et Entwicklung im Biotechnologiesektor, The rental price is not subject to Medikamentenentwicklung and Vermarktung eintritt.

InvestingPro-Tipps was founded by InvestingPro-Tipps, the Arbutus plus bargeld als Schulden in the biotechnology study house, which is financial flexibility for financing clinical studies and market sales opportunities. Darüber hinaus übersteigen die liquidn Mittel des Unternehmen die kurzfristigen Verpflichtungen, was auf eine solid finanzielle Position zur Unterstützung seiner Forschungsinitiativen hindeutet.

Investors are aware that strawberry tree operations are considered volatile, which is typical of biotechnology companies with chemicals in the investment sector. Das Unternehmen wird mit einem hohen Umsatz-Bewertungsmultiplikator gehandelt, was darauf hindeutet, ass die Markterwartungen für zukünftiges Wachstum sind sindifikant.

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