Welcome to Week 10 of the NFL season! We have four teams bye this week, so your start/sit decisions might be a little tougher than usual. I hope we can help you with some tips below.

If you like my advice, it won’t be difficult to transfer these thoughts into alignment decisions. As a basis I will use FantasyPros PPR Expert Consensus Rankings rankings as my guide. Here are your crucial roster decisions for Week 10.

Sam Darnold, Vikings at Jaguars

It’s generally not a difficult decision to start a quarterback against the Jaguars’ poor defense. Darnold has played quite well this season and it will likely be a nice peak week, especially with TJ Hockenson likely set to play a full complement of snaps to go along with a full stable of healthy wide receivers led by Justin Jefferson.

The Jaguars have allowed at least two touchdown passes to six quarterbacks this season. They also rank last in EPA pass defense and are second-worst in allowing fantasy points to quarterbacks. Start Darnold!

Brock Purdy, 49ers at Buccaneers

Purdy continues to post good efficiency numbers, but has struggled to find the end zone and avoid turnovers. The 49ers are coming off their bye and should be as healthy as they have been in a while. Christian McCaffrey is the big name who seems likely to return and his abilities as a receiver and runner make Purdy’s life much easier, especially around the goal line.

The 49ers are also expected to get Jauan Jennings back, who will need to play a bigger role with Brandon Aiyuk out for the season. Add in Deebo Samuel and George Kittle, and you have a group ready to put up numbers against the Buccaneers, who have allowed the most fantasy points to quarterbacks this season.

Drake Maye, Patriots at Bears

Maye proved to be a good option despite the weakness of the squad around him. Sure, he has some rookie issues, but he makes up for a lot of them with his legs, as Maye can fight with the best of them. That rushing ability keeps his potential higher than you might think, but this week he faces a Bears team that has allowed the fewest fantasy points to quarterbacks this season. He might still run enough to give him decent fantasy ground, but I’m sitting Maye in Chicago unless I’m desperate.

CJ Stroud, Texans vs. Lions

Stroud hasn’t been good this season but that’s definitely not his fault. His offensive line has been terrible and his receivers can’t stay on the field. Offseason addition Stefon Diggs is out for the season, while top receiver Nico Collins has missed the past four weeks with a hamstring injury. The hope was that Collins would return this week, but after not practicing on Wednesday or Thursday, it appears he will be out again.

The Lions also rank fifth in pass defense (EPA) and have not allowed a quarterback to throw more than one touchdown pass in a game. During the season, they allowed six touchdown passes and 11 interceptions in eight games. I’m moving away from Stroud.

Tyrone Tracy, Giants vs. Panthers

Tracy didn’t practice much last week while recovering from a concussion, so Devin Singetary took all those practice reps. But in the end, it didn’t matter, as Tracy was exonerated and continued to dominate the workload as leader. If you have any concerns with Tracy, you’re probably overthinking it this week.

The rookie faces the Panthers, and if you have a back against the Panthers, you start over. The Panthers have allowed the most rushing yards and the most touchdowns to running backs this season and they are not getting better as the season goes on.

Chuba Hubbard, Panthers vs. Giants

We’re still waiting to see if running back Jonothan Brooks will be active this week, but what we do know is that Chuba Hubbard will be after getting a nice new contract.

Brooks has been slow in his return from his college ACL injury and even if he plays this week, I would still start Hubbard like you have been all season. This Panthers team is not going to give their running back a big workload in their first game of a lost season – I’m confident of that. The Giants also rank 27th in EPA rushing defense this year.

Tony Pollard, Titans at Chargers

Pollard didn’t practice all last week, but ended up playing and playing well. He actually exceeded 30 touches against a weak Patriots defense. Unfortunately, he will have a much tougher game this week against the Chargers. Jim Harbaugh’s group has only allowed one rushing touchdown this year.

Tank Bigsby and Travis Etienne, Jaguars vs. Vikings

The Jaguars running backs are all healthy again, meaning their touches are split. The good news for Tank Bigsby is that he’s back in the lead role, but unfortunately, he needs a lead to keep him going. This has been tough for the Jaguars, as they have been mediocre on offense and mediocre on defense.

Additionally, it looks like Trevor Lawrence won’t be able to play against the Vikings. This should push Mac Jones to the lead, which is not good for the offense as a whole. Add in the tough Vikings defense, and I don’t like anyone in the Jaguars offense, including both running backs.

Jauan Jennings, 49ers at Buccaneers

All signs point to Jennings returning this week after the 49ers’ bye. This is good news for the 49ers passing attack, as Jennings has shown tremendous potential when targeted this year. The 49ers are healthier than they have been in some time, but wide receiver Brandon Aiyuk is out for the year, which should leave Jennings with enough work to be a fantasy contributor. And with the Buccaneers pass defense near the bottom in every category, I like his chances of putting up good numbers.

Rome Odunze, Bears vs. Patriots

It’s sad to see, but Keenan Allen is no longer the player he once was. What about DJ Moore? What do you do when you leave the field? I blame the BEars coaches for a lot of their problems, but I think Caleb Williams and fellow coach Rome Odunze are starting to get into rhythm. Last week, Williams targeted him seven times and he caught five of them for 104 yards. This week, they face a Patriots team that ranks 30th in EPA pass defense.

Calvin Ridley, Titans at Chargers

Ridley has too many targets to be completely down, but he has been extremely inconsistent. He now heads to Los Angeles to face a Chargers pass defense that ranks third in fantasy points allowed to receivers. It’s always worth starting where bye weeks make things difficult, but I have little confidence in him this week.

Marvin Harrison, Cardinals vs. Jets

Harrison has been inconsistent all season, but in his last five games he’s only had one where it was worth starting him in fantasy. It was a great game, where he had 111 yards and a touchdown against the Dolphins two weeks ago, but we don’t want to talk about the rest.

So far this season, he’s been a top-10 Fantasy receiver twice and he’s averaging just 6.1 targets per game. This week, he faces a Jets secondary that has allowed five touchdowns to wide receiver all season in nine games and the fewest receptions overall by a good margin.

Taysom Hill, Saints vs. Falcons

The Saints are suffering with Chris Olave out this week — and possibly more — with another head injury, Rashid Shaheed done for the season, and then numerous depth pieces at receiver and running back missing time. This should once again push Taysom Hill to good use this week. And when he gets a lot of snaps, he’s usually involved around the goal line.

Hunter Henry, Patriots vs. Bears

The Bears defense is tough on wide receivers, but they will let the tight ends take their checks. Drake Maye realized early that Henry was his safe space and I expect him to lead the team in targets this week as the Bears defense protects him from the big play.

Sam LaPorta, Lions at Texans

The Texans lead the league in receptions and yards allowed to tight ends this season. Additionally, Jameson Williams will be back from his suspension and Sam LaPorta is averaging a measly 3.3 goals per game this season. None of this sounds too promising.

Ja’Tavion Sanders, Panthers vs. Giants

Sanders has been putting up decent numbers lately and it makes sense to watch him with so many good tight ends goodbye. The good news is he’s catching big winners and proving he should continue to see more targets each week. But I’m worried about this game because the Giants lead the league in sacks and Bryce Young has been brutal under pressure this season. I think the Young-Sanders connection needs more time than Young can find in the pocket this week.